ChemArray

These novel high quality small molecule libraries are designed to produce better hit rates. They are built around biologically relevant, defined sub-structures which are necessary for ADME properties. Physically available in 3-15 mg quantities, the libraries are comprised of stable compounds. They are enriched with bioactive compounds and possess high chemical diversity. The libraries are closely related around clusters of novel compounds to improve patentability.

Using smaller molecules as molecular probes for specific protein targets enables these probes to bind to particular protein targets or enables targeting of families of proteins. This makes chemical diversity space more manageable. The compounds are then broken into fragments of molecules, which are then merged, or the fragments further elaborated in a manner unique to the ChemArrays™. This ChemArrays™ collection of libraries dramatically improve the chances of finding good starting points for the drug discovery cycle against novel drug targets, due to their inherent design.

Using highly trained scientists, and efficient and completely automated methods for synthesis, separation, purification and analysis, accelerate the creation of the ChemArrays™ collection of libraries, enabling a broad range of structures to be made. Based on a decade of research into the development of novel spirocyclic or bicyclic chemistry scaffolds and building blocks, the ChemArrays™ chemical libraries are truly unique and diverse with high levels of purity.